2011_10_22 anomie \AN-uh-mee\, noun: A sense of loneliness and anxiety

anomie \AN-uh-mee\, noun:
A sense of loneliness and anxiety; a state or condition characterized by a breakdown or absence of social norms and values, as in the case of uprooted people.

That Texas was a fluid situation which attracted people who were prone to anomie, and that in their continuing disorganization they killed themsevles.
-- James W. Michener, Texas

In particular, in his search to live up to his father's example, Oskar has to overcome the depressing sense of anomie that results from living in a big city.
-- Kristiaan Versluys, Out of the Blue

Anomie comes directly from the Greek anomia meaning lawlessness, from a (without) and nomia (law)